The National Palliative Care Research Center

Curing suffering through palliative care research.


Prasanna Ananth, MD, MPH

Assistant Professor

Yale University School of Medicine

Grant Year
Grant Term
2 years
Grant Type
Kornfeld Scholars Program

Project Description
Establishing Benchmarks for High Quality End-of-Life Care in Children with Cancer

There are currently no existing standards for high quality end-of-life care (EOLC) in children with cancer, contributing to high healthcare utilization for children with advanced cancer and widely variable palliative care provision. Consequently, children with cancer may receive EOLC that increases suffering and does not align with patient and family preferences. The long-term goal of Dr. Prasanna Ananth’s research program is to develop and implement evidence-based interventions that facilitate goal-concordant EOLC for children with cancer. The objectives in this proposal are to identify high priority family-centered EOLC quality measures and create a prospective questionnaire to assess care quality and experience for children with advanced cancer. To achieve these objectives, Dr. Ananth will pursue training in patient-centered, participatory research methods and questionnaire development. Dr. Ananth is supported by an outstanding mentorship team with collective expertise in health services, outcomes, and palliative care investigation. Her mentors will ensure successful completion of the research and learning objectives in this proposal and guide Dr. Ananth’s transition to independence. She is additionally supported by a team of collaborators and advisors with highly relevant methods expertise. The proposed work builds on Dr. Ananth’s preliminary studies and leverages this robust mentorship and training plan to advance the science of EOLC quality measurement in childhood cancer. In this proposal, Dr. Ananth aims to (1) Establish a priority list of EOLC quality measures, and (2) Develop and pilot a novel questionnaire to assess parent perceptions of care quality for children with advanced cancer. Completion of these aims will advance submission of an NIH K award and lay the foundation for the first multi-center, longitudinal evaluation of advanced cancer care quality in children. In sum, this research will serve as a springboard to launch Dr. Ananth’s career as an independent investigator in pediatric palliative oncology.


Prasanna Ananth, MD, MPH is an Assistant Professor of Pediatrics at the Yale School of Medicine. She received a BA degree in Human Biology from Stanford University, an MPH from the University of California, Berkeley, and a medical degree from Stanford School of Medicine. Following her pediatric training in the Boston Combined Residency Program, she completed pediatric hematology/oncology fellowship at Dana-Farber Cancer Institute and Boston Children’s Hospital. She joined the faculty at Yale in 2017, where she conducts research under the auspices of the Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center. Her family-centered research seeks to evaluate and enhance end-of-life care quality for children with cancer.